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Utilizing Pion's SiriusT3 Platform Webinar

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Utilizing Pion's SiriusT3 Platform Webinar

Webinar

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Dr. Rebeca Ruiz using the SiriusT3 which measures pKa, log P, log D and solubility of ionizable, small molecule drugs

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Dissolve Macro Orange

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Utilizing Pion's SiriusT3 Platform Webinar

Webinar

Dr. Rebeca Ruiz, Pion Analytical Services Manager, and Dr. Clara Rafols from the University of Barcelona present applications using the SiriusT3 which measures pKa, log P, log D and solubility of ionizable, small molecule drugs using sub-milligram quantities of sample.

Webinar

Dissolve Macro Orange
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Introduction to log P and log D measurement using PionT3
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The use of cosolvent pKa assays for poorly soluble compounds
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Measurement of Extreme pKas
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Surface dissolution imaging to investigate the influence of common ion effect on Papaverine hydrochloride
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Interplay between Ketoconazole Cocrystal Supersaturation and Trans-membrane Flux Behavior In Simulated Intestinal Fluids
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Application of In Situ Potentiometric Sensors to Study Dissolution-Precipitation Behavior of Electrospray-Generated Loperamide Nanoparticles
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Determination of the Intrinsic Dissolution Rate (IDR) from a Powder and using a Miniaturized Wood’s Apparatus
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Penetration Enhancer Effect of Sucrose Esters
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Prediction of Caco-2 pH-Dependent Permeability based on High Quality in vitro Training Set
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Comparison of Miniaturized Intrinsic Dissolution Rate Measurement to Traditional Wood’s Apparatus
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Novel in vitro PK (non-animal PK) Assay for Excipient/Vehicle Formulation Studies
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Drug Permeation in Skin PAMPA and Franz Cell Model
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In Situ Solubility and Dissolution of Concentrated Solutions
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Powder Intrinsic Dissolution Rate Measurement: When is it Possible?
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Prediction of in situ Blood-Brain Barrier Permeability using BBB PAMPA Model
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Impact of Biorelevant Media on Apparent Solubility and Biopharmaceutical Classification of Poorly Soluble Compounds
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Very Thin PAMPA Membranes Indicate Higher Antipyrene Permeability but are Fragile and Contain Leaky Water Pores
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Nanoparticle Formulation of Gresiofulvin
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Universal Potentiometric Sensors Protein Binding
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In Vitro-In Vivo Correlation (IVIVC): Prediction of pK a at 37°C, From the Measured Value at 25°C
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Human Jejunal Permeability Predicted from Caco-2 Assay - A Biophysical Model Applied to Fluoroquinolone Antimicrobials
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Novel Device and Method for in situ UV Dissolution and Precipitation Monitoring in 96-well Plate
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Evaluation of Optimized Caco-2 Permeability Measurements
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Developing Skin PAMPA for Transdermal Patches
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Supersaturation and Transmembrane Flux of Meloxicam
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Universal Potentiometric Sensors Food Matrixes
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Differentiating itraconazole formulations based on the flux through artificial lipophilic membranes
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Application of Skin Pampa to Cosmetic Solvent Screening
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Karl Box Sunrise Presentation
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Supersaturation in additives and GI fluids
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Determination of Polymer Effectiveness
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