Scientists in a lab conducting research

Bridging the gap between in vitro experiments and in vivo outcomes

Get better in vitro/in vivo correlation (IVIVC) and PhysioChemical Indicators for solubility, absorption and permeability.

Accelerate your pharmaceutical formulation development with next-generation technology. As a leading analytical instrument company, Pion supports your research with in vitro scientific instruments, analytical services and equipment to deliver the accuracy of results required for more predictive decision-making in the drug development process.

News: Pion Acquires Bee International

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News: Pion Acquires Two Square Science

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Introducing the Rainbow R6 Dynamic Dissolution Monitor® System

The Rainbow R6 is our newest in-situ fiber optic concentration monitoring system for dissolution testing, flux assays, solubility studies and other applications requiring high accuracy and repeatability in concentration measurement. The Rainbow R6 is the core of Pion’s integrated microDISS and miniDISS dissolution monitoring systems, used for early phase compound screening and studies with biorelevant volumes, and FLUX systems, which improve the assessment of absorption potential. It is available as a standalone instrument for USP baths or specialized applications.

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Subcutaneous Injection Site Simulator (SCISSOR)


Investigate the release performance of subcutaneous formulations with our SubCutaneous Injection Site SimulatOR (SCISSOR)

Assess the risk and performance of subcutaneously-administered drugs including biologics, peptides and small molecules.  Generate release profiles, simulate stress conditions and environmental transitions that can lead to precipitation/aggregation events, monitor drug stability upon injection and determine a rank order of different formulations.

The only commercially-available instrument that bridges the gap between standard dissolution and solubility results and in vivo Pharmacokinetic (PK) studies.

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See how our Analytical Services team can support you today!

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Pion Technology Drives Innovation

Pion scientific instruments support novel drug development in leading research centers around the world. As a leader in formulation sciences, we specialize in all aspects of pharmaceutical product development, from physchem analysis to clinical testing. We treat your goals like our own, helping position your product for greater therapeutic and commercial success. Advance your program with next-generation pharmaceutical development and technology.

Products at a glance

Products at a Glance

Looking for a specific dissolution apparatus, analytical instrument or in-vivo predictive tool? Here’s where you’ll find it.

Capabilities and applications

Dependable Servicing

Dependable Servicing

Servicing for Pion devices, including IQ/OQ, Preventive Maintenance, and Training. All maintained to manufacturer’s specifications and performance levels. Stay confident in your results and the productivity of your program.

Contract service or on-call

Analytical Services

Analytical Services

Our analysts can run a wide range of in-vivo predictive assays specialising in PhysChem and in-vivo prediction. As well as running standardised assays, we can also work with you in consultative partnership.

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About Pion

About Pion

We invest our profits into developing next-generation technology. See why.

The Pion story

Resource Library

Resource Library

See the latest industry citations of Pion instruments and services.

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News and events

Latest Events

See the latest events that Pion is supporting and attending.

All the latest



Pion’s quick response time to our service needs keeps downtime to a minimum in our lab.

QC Director

They truly care about the customer experience and the financial impacts on our company.

Company President

Pion’s service is the gold standard for our industry. They are in a league by themselves!

QC Supervisor
North Carolina

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Talk to Pion

Talk to Pion

What are your drug development challenges? Let us know and see how we can help.

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