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New and Exciting from Pion

 

An upcoming publication in the International Journal of Pharmaceutics investigates using the Parallel Artificial Membrane Permeation Assay (PAMPA) model to assess in vitro skin penetration of pharmaceutical or cosmetic ingredients without using human or animal tissue.

A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model

New research from the University of Kansas using Pion’s Scissor technology to test subcutaneous injections of Glatiramer Acetate, the active ingredient in Copaxone®, was published in the Journal of Controlled Release.

Glatiramer Acetate Persists at the Injection Site and Draining Lymph Nodes via Electrostatically-Induced Aggregation

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A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model
A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model
Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation
Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation
Using pH Gradient Dissolution with In-Situ Flux Measurement to Evaluate Bioavailability and DDI for Formulated Poorly Soluble Drug Products
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Studying semi-solid formulations of diclofenac using Skin PAMPA
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Degree and Extent of Supersaturation of Amorphous Pharmaceuticals and Their Flux through Lipophilic Membranes
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