Effects of drug-rich phase properties formed by liquid-liquid phase separation on the drug membrane permeability analyzed using μFLUX

In this application note, drug permeation studies using μFlux showed that the size of the drug-rich phase formed by LLPS strongly affects the membrane permeability of the drug. This study indicates that utilizing more highly supersaturated formulations capable of forming nanosized drug-rich phases improves drug absorption beyond the absorption improvement performance expected from the achievable supersaturation level of the drug. Download a copy to find out how.

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