Universal Potentiometric Sensors: Application for Real Time Concentration Monitoring in Complex Biorelevant Media

Up till present the use of universal potentiometric sensors in surfactant containing media was problematic. Typical issues arising are: slow response, limited sensitivity and short lifespan. In this study we will show that the free drug sensors can be used in media containing up to 5% surfactant and that the above mentioned issues can be satisfactory resolved. The products Brij-35 ® Tween 20 ® and Tween 80® were tested.