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The intrinsic solubility of indomethacin

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The intrinsic solubility of indomethacin

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Indomethacin has been described as “practically insoluble in water” [1]; solubilities between 2-7 µg/mL have been reported[2,3].

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Dissolve Macro Orange

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The intrinsic solubility of indomethacin

Poster

Purpose Indomethacin has been described as “practically insoluble in water” [1]; solubilities between 2-7 µg/mL have been reported[2,3]. However a higher value of 410 µg/mL has also been proposed [4]. Uncertainty undermines computational efforts to predict solubility [5]. Which value is correct?

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Dissolve Macro Orange
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