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Considerations on the potentiometric logP determination
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The titration of an ionizable compound in a biphasic system like octanol/water or liposome/water at various volume ratios r permits.
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The titration of an ionizable compound in a biphasic system like octanol/water or liposome/water at various volume ratios r permits the calculation of the true partition coeffiecients (P) (l) of all its ionization species.