resources

AuPRO™ 7 Software

View All Resources

Brochure

Preview - This content has been restricted to logged in users only.

AuPRO™ is Pion’s UV absorption data collection and refinement software for the Rainbow dynamic dissolution monitor

Login

Signup

View All Resources

Brochure

Features:

• Collects data from up to 8 individual fiber optic channels

• Each channel can measure different samples in different media

• Real-time concentration monitoring in each channel

• Diverse capabilities to deal with highly turbid solutions

• Multiple mathematical approaches to resolve the contribution of 2+ absorbing components

• Easy to use software platform

• Automated data processing capabilities

Brochure

4 Benefits to Conducting Simultaneous Dissolution and Permeability Experiments in Drug Development

Application Notes

Carbon Nanotube Application Test Data and Results

Application Notes

Conserving biorelevant enzymatic activity during in vitro subcutaneous drug testing

Brochure

DissoPro Software v3.6

Webinar

Webinar: LIVE DEMO! Taking in vitro Data to in vivo Prediction

Webinar

Advancements in hydrogel formats to model potential drug interactions occurring at the subcutaneous injection site

Brochure

Subcutaneous Injection Site Simulator Assay

Webinar

Advancements in hydrogel formats to model potential drug interactions occurring at the subcutaneous injection site

Brochure

Predictor Software

Brochure

Service agreement plans

Brochure

SiriusT3 Lite - A PhysChem Platform

Webinar

Predictive power and operational use of SCISSOR to streamline SC biologics drug development

Webinar

The impact of colloids and nanoparticles on intestinal drug absorption

Publication

Hydrogel formats to model potential drug interactions occurring at the subcutaneous injection site

Publication

Bioequivalence prediction with small-scale biphasic dissolution and simultaneous dissolution-permeation apparatus - An aripiprazole case study

Brochure

Micro DeBEE

Webinar

Demonstrating the excipient effect in vitro for subcutaneous pre-clinical formulation analysis

Whitepaper

Pion's BEE Brand Homogenizers - The Ultimate Research Tool

Application Notes

Effects of drug-rich phase properties formed by liquid-liquid phase separation on the drug membrane permeability analyzed using μFLUX

Whitepaper

Exploring the value of flux measurements in drug formulation and development: Bioavailability beyond dissolution rate alone. ADDF

Webinar

Introduction to Pion's BEE brand high-pressure homogenizers

Poster

Predicting the Relative In Vivo performance of Nanoformed and Crystalline Bulk Piroxicam Solid Suspensions from In Vitro Flux Measurements

Application Notes

Revisiting 2nd derivative UV spectroscopy for real-time monitoring of structural changes and complexations of macromolecules

Application Notes

Real time monitoring the extent of plasmid-liposome complexation using 2nd derivative fiber-optic UV spectroscopy

Application Notes

Development and characterization of an in vitro method for investigating pharmacokinetic behavior of long-acting subcutaneously injected therapeutics

Application Notes

Using NaOH and NaCl instead of KOH and KCl

Application Notes

Introduction to log P and log D measurement using PionT3

Application Notes

Measuring log P of samples that are hard to dissolve in water and octanol

Application Notes

The Determination of Solubility - Pion CheqSol Explained

Application Notes

The use of cosolvent pKa assays for poorly soluble compounds

Application Notes

Measurement of Extreme pKas

Application Notes

Solubility and Supersaturation - A Brief Introduction

Video

Scissor N3 overview and demo

Application Notes

Human Collagen’s Role within Artificial Extracellular Matrices used for in vivo Analysis of Injectable Formulations

Application Notes

Scissor as a platform for the analysis of non-protein subcutaneous formulations

Application Notes

Understanding excipient effect in vitro using the Pion Scissor

Application Notes

Considerations on the Controlled Release of Injectable Insulin Using Scissor

Application Notes

Scissor App Note_ECM-XR validation, peptides, mAbs, small molecules

E-book

How to Achieve Efficient & Consistent Particle Size Reduction e-book

E-book

Homogenization For Cannabis e-book

E-book

Advantages of BEE Homogenizers for the Pharmaceutical Industry e-book

E-book

7 Key Factors to Consider When Choosing A Cell Lysis Method - e-book

Publication

Reversal of IDO-mediated cancer immune suppression

Publication

Control of Oral Bioavailability by Particle Sizes

Publication

Method for preparing propofol emulsion for vascular injection

Publication

Development of Injectable PEGylated Liposome Encapsulating Disulfiram for Colorectal Cancer Treatment

Publication

Nanoparticle Formation

Brochure

DeBEE 4000

Webinar

Barriers and solutions for mimicking an in vivo extracellular environment with in vitro tools

Webinar

Creating consistency & predictability in cannabis-infused beverages - Vertosa and Pion Inc.

Poster

Surface dissolution imaging to investigate the influence of common ion effect on Papaverine hydrochloride

PrepEngine Demo: Chinese Traditional Medicine Sample Prep | Goji Berries & Baikal Skullcap Root

Poster

Interplay between Ketoconazole Cocrystal Supersaturation and Trans-membrane Flux Behavior In Simulated Intestinal Fluids

Poster

Application of In Situ Potentiometric Sensors to Study Dissolution-Precipitation Behavior of Electrospray-Generated Loperamide Nanoparticles

Poster

Cyclodextrin-Based Orally Fast Dissolving Drug Delivery System of Aripiprazole and Its In Vitro Dissolution-Permeation Testing Using µFLUX

Poster

Dissolution, Free Drug Concentration and Permeability of Crystalline Nanoparticle Formulation Study Using In Situ Fiber Optic and Potentiometric Techniques

Poster

Real Time Dissolution Monitoring of Dual Component Drug Product Using Fiber Optic System

Poster

MacroFLUX An Integration of Absorption Chamber with USP II Dissolution Apparatus

Poster

Dissolution Rate and Apparent Solubility of Poorly Soluble Compounds in Biorelevant Fluids

Poster

Universal Potentiometric Sensors Fast Determination of Free Ionized Drug Concentration in Micellar Solutions

Poster

Universal Potentiometric Sensors: Application for Real Time Concentration Monitoring in Surfactant Containing

Poster

Determination of the Intrinsic Dissolution Rate (IDR) from a Powder and using a Miniaturized Wood’s Apparatus

Poster

Penetration Enhancer Effect of Sucrose Esters

Poster

Prediction of Caco-2 pH-Dependent Permeability based on High Quality in vitro Training Set

Poster

Comparison of Miniaturized Intrinsic Dissolution Rate Measurement to Traditional Wood’s Apparatus

Poster

Novel in vitro PK (non-animal PK) Assay for Excipient/Vehicle Formulation Studies

Poster

Drug Permeation in Skin PAMPA and Franz Cell Model

Poster

In Situ Solubility and Dissolution of Concentrated Solutions

Poster

Powder Intrinsic Dissolution Rate Measurement: When is it Possible?

Poster

Prediction of in situ Blood-Brain Barrier Permeability using BBB PAMPA Model

Poster

Impact of Biorelevant Media on Apparent Solubility and Biopharmaceutical Classification of Poorly Soluble Compounds

Poster

Very Thin PAMPA Membranes Indicate Higher Antipyrene Permeability but are Fragile and Contain Leaky Water Pores

Poster

Nanoparticle Formulation of Gresiofulvin

Poster

Universal Potentiometric Sensors Protein Binding

Poster

In Vitro-In Vivo Correlation (IVIVC): Prediction of pK a at 37°C, From the Measured Value at 25°C

Poster

Human Jejunal Permeability Predicted from Caco-2 Assay - A Biophysical Model Applied to Fluoroquinolone Antimicrobials

Poster

Novel Device and Method for in situ UV Dissolution and Precipitation Monitoring in 96-well Plate

Poster

Evaluation of Optimized Caco-2 Permeability Measurements

Poster

Developing Skin PAMPA for Transdermal Patches

Poster

Supersaturation and Transmembrane Flux of Meloxicam

Poster

Universal Potentiometric Sensors Food Matrixes

Poster

Preparation, Physical Characterization and Solubility-Dissolution Testing of Loratidine Hot Melt Extrudates Prepared on a Laboratory Mixing Extruder

Poster

Evaluating Drug Salt Dissolution and Precipitation Processes for Rational Formulation Strategies

Poster

Skin-PAMPA: A New Method for Fast Prediction of Skin Penetration

Poster

Monitoring Supersaturation State of Solid Dispersions of Low Solubility Compounds

Poster

Skin-PAMPA: Fast Prediction of Skin Penetration

Poster

Comparison of Naproxen Release from Nano- and Microsuspensions with Its Dissolution from Untreated and Micronized Powder

Poster

Soluplus® Maintains the Supersaturation of Carbamazepine from Amorphous Solid Dispersions

Poster

In Situ Monitoring of Supersaturation State for Solid Dispersions of Low Soluble Compounds

Poster

Application of Skin PAMPA to Differentiate Between Topical Pharmaceutical Formulations of Ibuprofen

Poster

Dissolution and Precipitation Monitoring of Crystalline Salts

Poster

Assessment of Transdermal Penetration Enhancement by Topical Pharmaceutical Excipients Using Skin PAMPA Method

Poster

Universal Potentiometric Sensors: Application for Real Time Concentration Monitoring in Complex Biorelevant Media

Poster

Real Time Monitoring of Dissolution, Supersaturation and Precipitation Processes in Dynamically Changing Biorelevant Media

Poster

Dissolution-Permeability Apparatus with Integrated In Situ Concentration Monitoring of both Donor and Receiver Compartments

Poster

Novel HT Method for Parallel Excipient/Vehicle Formulation Studies