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Parallel Artificial Membrane Permeability Assay (PAMPA) Platform - Product Sheet

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Parallel Artificial Membrane Permeability Assay (PAMPA) Platform - Product Sheet

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PAMPA is a high-throughput platform for assessing drug permeability using artificial membranes that mimic drug uptake under gastro-intestinal conditions (GIT).

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Dissolve Macro Orange

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Parallel Artificial Membrane Permeability Assay (PAMPA) Platform - Product Sheet

Brochure

PAMPA is a high-throughput platform for assessing drug permeability using artificial membranes that mimic drug uptake under gastro-intestinal conditions (GIT), across the blood-brain barrier (BBB) or through the human skin. It provides robust, reliable, and relevant results that support preformulation screening, and for the evaluation/comparison of complex formulations.

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Dissolve Macro Orange
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Prediction of Caco-2 pH-Dependent Permeability based on High Quality in vitro Training Set
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Comparison of Miniaturized Intrinsic Dissolution Rate Measurement to Traditional Wood’s Apparatus
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Novel in vitro PK (non-animal PK) Assay for Excipient/Vehicle Formulation Studies
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Drug Permeation in Skin PAMPA and Franz Cell Model
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In Situ Solubility and Dissolution of Concentrated Solutions
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Powder Intrinsic Dissolution Rate Measurement: When is it Possible?
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Prediction of in situ Blood-Brain Barrier Permeability using BBB PAMPA Model
Poster
Impact of Biorelevant Media on Apparent Solubility and Biopharmaceutical Classification of Poorly Soluble Compounds
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Very Thin PAMPA Membranes Indicate Higher Antipyrene Permeability but are Fragile and Contain Leaky Water Pores
Poster
Nanoparticle Formulation of Gresiofulvin
Poster
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Human Jejunal Permeability Predicted from Caco-2 Assay - A Biophysical Model Applied to Fluoroquinolone Antimicrobials
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Novel Device and Method for in situ UV Dissolution and Precipitation Monitoring in 96-well Plate
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Evaluation of Optimized Caco-2 Permeability Measurements
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Developing Skin PAMPA for Transdermal Patches
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Supersaturation and Transmembrane Flux of Meloxicam
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Preparation, Physical Characterization and Solubility-Dissolution Testing of Loratidine Hot Melt Extrudates Prepared on a Laboratory Mixing Extruder
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Evaluating Drug Salt Dissolution and Precipitation Processes for Rational Formulation Strategies
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Skin-PAMPA: A New Method for Fast Prediction of Skin Penetration
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Monitoring Supersaturation State of Solid Dispersions of Low Solubility Compounds
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Skin-PAMPA: Fast Prediction of Skin Penetration
Poster
Comparison of Naproxen Release from Nano- and Microsuspensions with Its Dissolution from Untreated and Micronized Powder
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Soluplus® Maintains the Supersaturation of Carbamazepine from Amorphous Solid Dispersions
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In Situ Monitoring of Supersaturation State for Solid Dispersions of Low Soluble Compounds
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Application of Skin PAMPA to Differentiate Between Topical Pharmaceutical Formulations of Ibuprofen
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Dissolution and Precipitation Monitoring of Crystalline Salts
Poster
Assessment of Transdermal Penetration Enhancement by Topical Pharmaceutical Excipients Using Skin PAMPA Method
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Universal Potentiometric Sensors: Application for Real Time Concentration Monitoring in Complex Biorelevant Media
Poster
Real Time Monitoring of Dissolution, Supersaturation and Precipitation Processes in Dynamically Changing Biorelevant Media
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