Rainbow

Biorelevant Dissolution techniques can establish more accurate correlations between in-vitro and in-vivo outcomes then using conventional USP baths alone. Rainbow’s world-class optical technology is increasingly regarded as a key tool in dissolution investigations.

Ten of the world’s top ten pharmaceutical companies use Pion’s fibre-optic technology to support dissolution measurement.

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Overview

The Rainbow dynamic dissolution monitor is a powerful analytical instrument that correctly and accurately measures dissolution in real time. This makes it an ideal partner in biorelevant dissolution investigations. Rainbow will produce consistent, replicable results, whatever the prandial media.

Built with a world-class optical bench, Rainbow allows for the simultaneous analysis of up to 8 vessels as fast as every 2 seconds. That means your variables can be tested more efficiently, more quickly, and to a greater degree of accuracy.

Applications

  • Real-time analysis of dissolution progress, regardless of dissolution media
  • Generates more detailed profiles
  • Simultaneous analysis for screening formulations ahead of bio-equivalence studies

Features

Individual diode array spectrometers

Programmable data collection of the entire UV spectrum, as fast as every two seconds.

8 dip-style probes

Rugged and robust stainless-steel construction for longer life and easier cleaning.

User-friendly graphic interface

For real-time data collection and analysis.

Resources

Extended Instrument Shut Down for Pion Rainbow Storage Guidelines

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Evaluating side‐by‐side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine

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Release notes - DissoPro 3.5

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In Situ Fiber Optic Dissolution Monitoring of Combination Drug Product Containing Three Actives

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From Traditional Dissolution to In Vivo Predictive Flux Measurements

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Biorelevant Flux Measurements And Prediction Of Fraction Absorbed For The Drug Products Of Poorly Soluble Compounds

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Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states

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Mechanistic Study of Belinostat Oral Absorption From Spray-Dried Dispersions

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In situ fiber optic dissolution monitoring of vitamin B12 solid dosage formulation

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Rainbow Brochure

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Accessories Mesh Brochure

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Accessories 30 Degrees Brochure

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Application of MacroFLUX™ Apparatus for Screening Formulations before Bioequivalent Studies

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Using Integrated Absorption Chamber with USP II Dissolution Apparatus to Predict Risk of Drug-Drug Interaction from pH Modifying Agents: Poster

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Application of simultaneous dissolution-absorption apparatus for screening formulations before bioequivalence studies

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MacroFLUX An Integration of Absorption Chamber with USP II Dissolution Apparatus

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Real Time Dissolution Monitoring of Dual Component Drug Product Using Fiber Optic System

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Products at a glance

Products at a glance

Check out the specifications and capabilities of Pion equipment.

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Analytical Services

Analytical Services

Our analysts run standard tests and assays for you on Pion equipment or serve as consultative partners.

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Resource Library

Resource Library

Latest citations of Pion instruments and services in industry white papers, webinars, videos, and case studies.

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Pion's quick response time to our service needs keeps downtime to a minimum in our lab.

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