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In Vivo Predictive Tools

The role of biopharmaceutical analysis has grown rapidly in the past 30 years, driven by the discovery of new molecules and innovative therapies. However, drug form and formulation can both impact on release and absorption, and scientists need new ways to understand and predict these effects. Pion is a true pioneer in this area, with an innovative and ever-growing range of specialist instruments.

AbsorptionPermeabilitySolubilitySubcutaneousSurface Imaging

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MacroFLUX™ for Absorption

Assess the dissolution of finished drug product simultaneously with absorption potential for more predictive IVIVC modelling.

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MicroFLUX for Absorption

Pion’s dissolution-permeability apparatus for the simultaneous assessment of formulation drug release and absorption.

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inForm for Absorption

A powerful and versatile formulation workstation for automated analysis of solutions, powders, suspensions, compacted pellets and dosages in situ.

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BioFLUX for Absorption

BioFLUX extends the utility of in-situ UV fiber-optic concentration monitoring, using biorelevant dissolution volumes of 200-250mL.

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PAMPA for Permeability

An efficient high-throughput tool to measure passive transmembrane permeability and flux – skin, blood-brain, and GIT.

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Gut-Box for Permeability

A special stirring device that improves the accuracy and reliability of your PAMPA solubility and permeability assays.

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TempPlate for Permeability

TempPlate A simple cost-effective solution for accurate temperature control during plate incubation, with straightforward touchscreen controls.

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MicroDISS Profiler for Solubility

Pion’s in-situ fiber optic monitoring system provides real-time concentration monitoring.

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SiriusT3 for Solubility

A fully automated tool for compound screening and PhysChem analysis, using Pion’s proprietary CheqSol method.

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inForm for Solubility

A powerful and versatile instrument for automated analysis of solutions and formulations in-situ.

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Scissor for Subcutaneous

Designed specifically to assess the risk and performance of subcutaneously administered drugs including biologics, peptides and small molecules.

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SDi2 for Surface Imaging

Real-time imaging of the dissolution process for maximum insight.

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Products at a glance

Products at a glance

Check out the specifications and capabilities of Pion equipment.

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Analytical Services

Analytical Services

Our analysts run standard tests and assays for you on Pion equipment or serve as consultative partners.

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Resource Library

Resource Library

Latest citations of Pion instruments and services in industry white papers, webinars, videos, and case studies.

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Pion's quick response time to our service needs keeps downtime to a minimum in our lab.

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