The role of biopharmaceutical analysis has grown rapidly in the past 30 years, driven by the discovery of new molecules and innovative therapies. However, drug form and formulation can both impact on release and absorption, and scientists need new ways to understand and predict these effects. Pion is a true pioneer in in vitro drug testing, with an innovative and ever-growing range of specialist instruments.
Pion’s smart in vitro testing and imaging systems are designed to expedite pharmaceutical development. They can help assess the absorption of APIs, monitor solubility, and provide invaluable insights into the dissolution process.
Save time and minimize costly errors with our top-of-the-line in vitro technologies.
Assess the dissolution of finished drug product simultaneously with absorption potential for more predictive IVIVC modelling.
Pion’s dissolution-permeability apparatus for the simultaneous assessment of formulation drug release and absorption.
A powerful and versatile formulation workstation for automated analysis of solutions, powders, suspensions, compacted pellets and dosages in situ.
BioFLUX extends the utility of in-situ UV fiber-optic concentration monitoring, using biorelevant dissolution volumes of 200-250mL.
An efficient high-throughput tool to measure passive transmembrane permeability and flux – skin, blood-brain, and GIT.
A special stirring device that improves the accuracy and reliability of your PAMPA solubility and permeability assays.
TempPlate A simple cost-effective solution for accurate temperature control during plate incubation, with straightforward touchscreen controls.
Pion’s in-situ fiber optic monitoring system provides real-time concentration monitoring.
A fully automated tool for compound screening and PhysChem analysis, using Pion’s proprietary CheqSol method.
A powerful and versatile instrument for automated analysis of solutions and formulations in-situ.
Designed specifically to assess the risk and performance of subcutaneously administered drugs including biologics, peptides and small molecules.
Real-time imaging of the dissolution process for maximum insight.
In vivo imaging is a non-invasive technique used to peer deep into the internal systems of living organisms for diagnostic or research processes. By using special analytical instruments, researchers can analyze complex biological processes in plants, animals, or humans.
In vitro imaging can provide valuable insights for preclinical studies. From improving treatment response to assessing product safety, In vitro make the process of bringing a new pharmaceutical drug to the market faster and easier.
In vitro imaging provides a comprehensive picture of the biological effects of a drug or treatment. The organism is kept alive meaning future analysis can be performed on the same subject. In addition, real-time biological changes can be detected and followed. In vitro imaging also involves a generally undisturbed process which helps in producing more accurate results.
The term ‘in vivo’ refers to a test, study, or procedure that is performed within a living organism while “in vitro” describes activity that is done outside of a living organism.
In vivo pharmacology is the study of the biological effects of a compound on an organism. It can help researchers assess how diseases or tissues will respond to a certain drug.
In vitro testing and imaging tools can accelerate your research by delivering swift, precise, and cost-effective results.
Organizations rely on us for accurate tests, assays, analysis, and interpretation needed throughout the drug development process.
By using Pion equipment, problems with dissolution, solubility, permeability, and absorption can be detected earlier, saving valuable time and resources.
Pion's quick response time to our service needs keeps downtime to a minimum in our lab.