AuPRO™ is Pion’s comprehensive data collection and refinement software. It provides today’s drug development scientists with new ways to analyze kinetic solubility and dissolution data and to make the data refinement process more capable and efficient.
The latest version, AuPRO 6, offers scientists a range of new features to enhance compound analysis and to secure their system and is Windows 10 compatible.
The software is now modular, with three modules activated individually:
Basic Module - Allows basic dissolution experiments limited to one component
Standard Module - All functionality of the Basic Module plus features similar to AuPro software version 5.5.3, such as up to two components, ZIM analysis and advanced baseline correction
Additionally, the Standard Module has:
Advanced Module - All functionality of the Standard Module plus enabling resolution of up to four absorbing components using linear regression analysis, reconstructing and saving standards for nanoparticles, calculating and exporting flux values from the software
Additionally, the Advanced Module has:
AuPRO™ provides a number of insightful ways to analyze data:
Implementation of ZIM, an application of second derivative spectroscopy or linear regression analysis, can account for the presence of multiple absorbing components within the same matrix. In addition, multi-component concentration monitoring allows multiple standard curves to be used for the analy-sis of multi-component systems.
Spectral shape analysis enables detection of spectral changes between standard and sample spectra due to pH, degradation or other chemical in situ phenomena.
When used in conjunction reference channel and the Media change manager allows for a single data file to have multiple media addition steps, while accurately calculating concentration and % dissolved.
Photo Diode Array Spectrometers allow for collection of entire UV spectral range from every channel at every time point.
Degree and Extent of Supersaturation of Amorphous Pharmaceuticals and Their Flux through Lipophilic Membrane
In Situ Fiber Optic Dissolution Monitoring of Combination Drug Product Containing Three Actives
Webinar: AuPRO™ Version 6.0: New Powerful Tools for Pion’s Fiber Optic Users
AuPRO Comparison Flyer
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