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Rainbow

The UV fiber optic-based Rainbow® Dynamic Dissolution Monitor is a powerful tool, designed to deliver the fastest path to accurate dissolution analysis. Built with a world-class optical bench, it allows for simultaneous real-time data collection and analysis of up to 8 vessels through a user-friendly software interface.Its a detection core of the MicroDISS Profiler. 

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Overview

With 20 years of proven efficiency, Pion’s Rainbow® serves as the benchmark for in situ dissolution monitoring and is widely used throughout the industry. Researchers engaged in USP dissolution and those using more novel apparatus can utilize this powerful tool to improve throughput, reduce consumables, eliminate waste streams and provide more detailed profiles. The Rainbow® also eradicates clogging, leaking and the need for pump maintenance thanks to its ability to ‘pump the light, not the liquid’.

Applications

  • Traditional dissolution
  • Small volume dissolution – tablets and powder
  • Nanoparticle dissolution
  • Intrinsic dissolution and rank order intrinsic dissolution
  • USP and EU dissolution
  • Biorelevant dissolution media
  • Excipient screening
  • Salt screening
  • Stability monitoring
  • Media pH change
  • Dynamic media change
  • Detect polymorphic changes
  • Supersaturation studies
  • Solubility – Aqueous and Non-Aqueous
  • Follow stability profiles
  • Track supersaturation effects
  • Determine equilibrium solubility
  • Biphasic Dissolution
  • Artificial stomach duodenum monitoring

Features

Robust

The Rainbow’s dip style probes and interchangeable reflectance tips are engineered from stainless steel, with a horizontal analysis path available through the J style dip probe.

Flexible

Variable path lengths of 1, 2, 5, 10 or 20 mm for maximum flexibility.

Cost-effective

Fast return on investment due to low maintenance cost, automated data collection, and enhanced capability

Fast

Up to 8 individual Photo Diode Array Spectrophotometers allows data collection of  UV/VIS spectra (200 – 720 nm) at 1nm resolution as often as every two seconds from all vessels simultaneously.

Versatile

Up to 8 data acquisition channels

Resources

In Situ Fiber Optic Dissolution Monitoring of Combination Drug Product Containing Three Actives

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From Traditional Dissolution to In Vivo Predictive Flux Measurements

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Biorelevant Flux Measurements And Prediction Of Fraction Absorbed For The Drug Products Of Poorly Soluble Compounds

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Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states

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Mechanistic Study of Belinostat Oral Absorption From Spray-Dried Dispersions

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In situ fiber optic dissolution monitoring of vitamin B12 solid dosage formulation

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Rainbow Brochure

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Accessories Mesh Brochure

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Accessories 30 Degrees Brochure

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Application of MacroFLUX™ Apparatus for Screening Formulations before Bioequivalent Studies

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Using Integrated Absorption Chamber with USP II Dissolution Apparatus to Predict Risk of Drug-Drug Interaction from pH Modifying Agents: Poster

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Application of simultaneous dissolution-absorption apparatus for screening formulations before bioequivalence studies

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MacroFLUX An Integration of Absorption Chamber with USP II Dissolution Apparatus

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Real Time Dissolution Monitoring of Dual Component Drug Product Using Fiber Optic System

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Consumables

Tip 1 mm Pathlength (RH)

112292

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Tip 2 mm Pathlength (RH)

112293

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Tip 5 mm Pathlength (RH)

112294

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Tip 10 mm Pathlength (RH)

112295

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Tip 20 mm Pathlength (RH)

112296

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Probe Standard Length 14cm (RH)

112298

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Probe Extended Length 31cm (RH thread)

120807

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Probe J Style variable tip

120859

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Tip C-Style 5 mm (RH)

121094

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Tip C-Style 10 mm (RH)

121095

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Tip C-Style 20 mm (RH)

121096

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Tip C-Style 2 mm (RH)

121097

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Probe Extended Length 31cm (LH thread)

112035

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Tip 1 mm Pathlength (LH)

112029

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Tip 2 mm Pathlength (LH)

112030

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Tip 5 mm Pathlength (LH)

112031

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Tip 10 mm Pathlength (LH)

112032

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Tip 20 mm Pathlength (LH)

112033

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Power Cord

100018

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Probe Adapter - Universal

112013

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Probe Adapter - J Style

120809

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FO Probe Vessel Cover

120792

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Fibre Optic Probe Mesh Covers

120780

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Standardization Station with Magnetic Stirrer - J Probe

120929

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Standardization Station with Magnetic Stirrer - Straight Probe Style

112168

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MiniBath 8 Position Probe Holder

112164

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USB Cable (External)

112305

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Analytical Services

Analytical Services

We can run your research for you.

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Products at a glance

Products at a glance

Check out the specifications and capabilities of Pion equipment.

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Analytical Services

Analytical Services

Our analysts run standard tests and assays for you on Pion equipment or serve as consultative partners.

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Resource Library

Resource Library

Latest citations of Pion instruments and services in industry white papers, webinars, videos, and case studies.

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Pion's quick response time to our service needs keeps downtime to a minimum in our lab.

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Tennessee

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