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Rainbow

Biphasic Dissolution techniques can establish more accurate correlations between in-vitro and in-vivo outcomes than conventional dissolution methods alone. Rainbow’s world-class optical technology is increasingly regarded as a key tool in biphasic dissolution investigations.

Ten of the world’s top ten pharmaceutical companies use Pion’s fibre-optic technology to support biphasic dissolution measurement.

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Overview

The Rainbow dynamic dissolution monitor is a powerful analytical instrument that correctly and accurately measures dissolution in real time. This makes it an ideal partner in biphasic dissolution investigations. Rainbow will produce consistent, replicable results, whatever the biphasic dissolution media.

Built with a world-class optical bench, Rainbow allows for the simultaneous analysis of up to 8 vessels as fast as every 2 seconds. That means all your biphasic variables can be tested more efficiently, more quickly, and to a greater degree of accuracy.

Applications

  • Real-time analysis of dissolution progress, regardless of dissolution media
  • Generates more detailed profiles
  • Simultaneous analysis for screening formulations ahead of bio-equivalence studies

Features

Individual diode array spectrometers

Programmable data collection of the entire UV spectrum, as fast as every two seconds.

8 dip-style probes

Rugged and robust stainless-steel construction for longer life and easier cleaning.

User-friendly graphic interface

For real-time data collection and analysis.

Resources

Impact of Gastric pH Variations on the Release of Amorphous Solid Dispersion Formulations Containing a Weakly Basic Drug and Enteric Polymers

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Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

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Advanced in vitro methods in generic drug product development

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Release notes - DissoPro 3.6 software for the Rainbow UV in-situ concentration monitor

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AuPRO 7.0

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"miniDISS Profiler Including the *NEW* miniDT" Webinar

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"Pion MacroFLUX for Predictive Dissolution Absorption Measurements" Webinar

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"Pion Biphasic Dissolution PBPK Modelling and Lipolysis Assays" Webinar

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Extended Instrument Shut Down for Pion Rainbow Storage Guidelines

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Evaluating side‐by‐side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine

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In Situ Fiber Optic Dissolution Monitoring of Combination Drug Product Containing Three Actives

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From Traditional Dissolution to In Vivo Predictive Flux Measurements

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Biorelevant Flux Measurements And Prediction Of Fraction Absorbed For The Drug Products Of Poorly Soluble Compounds

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Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states

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Mechanistic Study of Belinostat Oral Absorption From Spray-Dried Dispersions

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In situ fiber optic dissolution monitoring of vitamin B12 solid dosage formulation

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Accessories Mesh Brochure

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Accessories 30 Degrees Brochure

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Application of MacroFLUX™ Apparatus for Screening Formulations before Bioequivalent Studies

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Using Integrated Absorption Chamber with USP II Dissolution Apparatus to Predict Risk of Drug-Drug Interaction from pH Modifying Agents: Poster

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Application of simultaneous dissolution-absorption apparatus for screening formulations before bioequivalence studies

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MacroFLUX An Integration of Absorption Chamber with USP II Dissolution Apparatus

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Real Time Dissolution Monitoring of Dual Component Drug Product Using Fiber Optic System

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Rainbow Brochure

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Consumables

Tip 1 mm Pathlength (RH)

112292

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Tip 2 mm Pathlength (RH)

112293

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Tip 5 mm Pathlength (RH)

112294

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Tip 10 mm Pathlength (RH)

112295

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Tip 20 mm Pathlength (RH)

112296

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Probe Standard Length 14cm (RH)

112298

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Probe Extended Length 31cm (RH thread)

120807

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Probe J Style variable tip

120859

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Tip C-Style 5 mm (RH)

121094

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Tip C-Style 10 mm (RH)

121095

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Tip C-Style 20 mm (RH)

121096

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Tip C-Style 2 mm (RH)

121097

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Probe Extended Length 31cm (LH thread)

112035

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Tip 1 mm Pathlength (LH)

112029

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Tip 2 mm Pathlength (LH)

112030

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Tip 5 mm Pathlength (LH)

112031

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Tip 10 mm Pathlength (LH)

112032

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Tip 20 mm Pathlength (LH)

112033

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Power Cord

100018

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Probe Adapter - Universal

112013

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Probe Adapter - J Style

120809

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FO Probe Vessel Cover

120792

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Fibre Optic Probe Mesh Covers

120780

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Standardization Station with Magnetic Stirrer - J Probe

120929

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Standardization Station with Magnetic Stirrer - Straight Probe Style

112168

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MiniBath 8 Position Probe Holder

112164

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USB Cable (External)

112305

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Analytical Services

Analytical Services

We can run your research for you.

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Products at a glance

Products at a glance

Check out the specifications and capabilities of Pion equipment.

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Analytical Services

Analytical Services

Our analysts run standard tests and assays for you on Pion equipment or serve as consultative partners.

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Resource Library

Resource Library

Latest citations of Pion instruments and services in industry white papers, webinars, videos, and case studies.

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Pion's quick response time to our service needs keeps downtime to a minimum in our lab.

QC Director
Tennessee

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