Dissolution

MicroDISS

Insitu fiber optic UV monitoring system for small volumes of 2- 20 ml

MicroDISS Profiler ImageMicroDISS Profiler ImageMicroDISS Profiler Image
MicroDISS Profiler ImageMicroDISS Profiler ImageMicroDISS Profiler Image
benefits

Insitu fiber optic UV monitoring system for small volumes of 2- 20 ml

Designed to monitor concentration in real-time

Powered by AuPRO™

Most comprehensive dissolution data analysis software in the industry

Evaluate solubility, intrinsic disc dissolution rate, dissolution profiles, supersaturation, precipitation patterns

User-friendly graphic display

Simultaneous real-time data collection and analysis

MicroDISS

Configurations

Applications

The microDISS Profiler™ can be used to bring greater accuracy

  • Small volume dissolution – tablets, capsules, powders and films
  • Intrinsic dissolution of miniaturized compressed pellets
  • Biorelevant dissolution
  • Excipients and salts screening
  • Dynamic media composition change
  • Polymorphic changes and precipitation patterns
  • Intrinsic and Kinetic Solubility in – Aqueous and Non-Aqueous Media
  • Solution stability of drug candidates
  • Nanoparticle solubility and dissolution
  • Supersaturation studies
  • Micro- and nanonization effects on dissolution
The microDISS Profiler™ can be used to bring greater accuracy
The microDISS Profiler™ can be used to bring greater accuracy

Features

Features

Versatile
Smart software and flexible architecture allow for multiple experimental conditions on a single platform.

Robust
The MicroDISS Profiler™ employs dip-style probes engineered in stainless steel.

Fast and Accurate
Up to 8 individual Photo Diode Array Spectrophotometers allow data collection of UV/VIS spectra (200 – 720 nm) at 1nm resolution as often as every two seconds from all vessels simultaneously. Allows to work with variety of volumes and stirring speeds within a single experimental set up.

Cost-effective
Ideal for small volume dissolution (2-20 mL), with interchangeable pathlength tips to bring the cost-efficiencies of combined speed and flexibility.