Pion has developed a two-stage dissolution assay that simulates the transfer of a drug from stomach to intestine. This can reveal the influence of changing pH conditions on a drug’s behavior.
Pion can characterise dissolution and solubility behaviour in biorelevant media simulating different zones and compositions within the human body.
Surface dissolution imaging can accelerate your formulation development by revealing the disintegration characteristics of drug dosage forms.
Our analysts run Compendial Dissolution tests for you on Pion equipment or serve as consultative partners.
With Pion’s MacroFLUX™ device, you can reliably test and rank the absorption potential of formulations in-vitro to greatly enhance in-vivo prediction.
Pion’s BioFLUX™ accurately assesses the absorption potential of finished dosage forms under biorelevant conditions, greatly enhancing IVIVC modelling.
Pion can investigate the bioavailability of subcutaneous or intraocular formulations in vitro, using our novel Scissor instrument.