Conventional dissolution techniques allow scientists to establish the core properties of compounds under investigation but can be less effective when it comes to IVIVC prediction. That’s because in-vivo conditions vary with the progress of a drug through the human body.
Biphasic dissolution involves adding additional mediums to the standard monophasic model, allowing for much more sophisticated modelling of in-vivo conditions, and a corresponding improvement in IVIVC outcomes. Biphasic dissolution can allow scientists to develop much more reliable models of drug performance, before having to move to animal testing or clinical trials. As a leading facilitator of next-generation, Pion has naturally developed several instruments to support this increasingly important avenue of research.
A powerful and versatile formulation workstation for automated analysis of solutions, powders, suspensions, compacted pellets and dosages in situ.
Pion’s benchmark tool for in situ dissolution monitoring, designed to deliver the fastest path to accurate analysis.