miniDISS Profiler

The miniDISS Profiler™ is a Rainbow in situ Fiber Optic UV monitoring system with the miniDT dissolution tester and is designed for biorelevant media volumes. It is ideal for measuring high-potency API or when low concentrations are expected, typical of Pre-Formulation and Formulation activities.

Designed to work with the Pion Rainbow Dynamic Dissolution Monitor, the miniDT Dissolution Tester may be used independently.

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Overview

The miniDISS Profiler™ is Pion’s industry recognized Rainbow Fiber Optic UV-vis platform technology with a small volume dissolution tester for testing biorelevant volumes using vessels of 100-250 ml. It is ideal for measuring high-potency API or when low concentrations are expected and can be used to evaluate solubility, dissolution profiles, supersaturation, precipitation profile and more, with simultaneous real-time data collection and analysis and a powerful yet user-friendly graphic display.

Designed to work with the Pion Rainbow Dynamic Dissolution Monitor, the miniDT Dissolution Tester may be used independently.

Applications

  • Formulation development

  • Oral dosage form dissolution for sink and non-sink conditions
  • Pediatric drug products development
  • High potency drug products testing
  • Biorelevant volumes

Features

Flexibility in small volume testing

  • Eliminates time-consuming swap out and revalidation requirements when switching from large to small volumes
  • Eight-position stirring system with interchangeable 100 ml, 150 ml or 200 ml standard vessels or 250 ml Chinese Pharmacopiea vessels

Industry standard Rainbow technology

  • Data collection of the full UV Spectra (200 - 720 nm) as fast as every two seconds
  • Dip-Style Fiber Optic Probes with interchangeable path length tips

Consumables

Hose Kit for miniDT Bath

121439

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Heater Circulator, 115V/60 Hz

121521

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Heater Circulator, 230V/50 Hz with EU Plug

121522

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Heater Circulator, 230V/50 Hz with UK Plug

121523

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Immersion Heater, 115VAC/60 Hz

121524

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Immersion Heater, 230VAC/50 Hz

121525

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Immersion Heater, 230VAC/50 Hz with UK Plug

121526

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miniDT Basket Shaft for 100 - 250 mLvessels, 316 SS, serialized

121527

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miniDT Basket for 100 - 250 mL vessels, 316 SS, serialized

121528

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100 mL Vessel, clear glass, serailized

121529

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150 mL Vessel, clear glass, serialized

121530

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200 mL Vessel, clear glass, serialized

121531

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250 mL Vessel, Chinese Pharmacopeia, clear glass, serialized

121532

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Resources

miniDISS Profiler Brochure

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