Dissolution
Dissolution analysis is crucial to effective drug development. Yet traditional dissolution methods can be inefficient and time-consuming, delaying progress and consuming resources. Pion devices are engineered for versatility. Our in-situ solutions are used by fifteen of the top fifteen pharmaceutical companies for rapid, cost-effective, predictive results aligned to today’s drug development methodology.
Work with Pion on your Pre-formulation dissolution challenges, and our experts will run your dis-solution tests on our equipment – sharing the results, insight and analysis with you.
Dissolution Analytical Services
Miniaturised Dissolution
Miniaturized dissolution assays can help scientists make decisions during early stages of the drug development cycle – from pure API to early formulation strategies.
MicroFLUX
MicroFLUX™ allows you to combine data from a dissolution experiment with transmembrane permeation. It is the perfect in vitro tool to support pharmacokinetic (PK) prediction and decision-making.
IDR
Pion’s miniature dissolution equipment is capable of measuring the Intrinsic Dissolution Rate (IDR) for solid compounds you submit for analysis and has applications in ranking candidates during salt selection and solid form screening.
IDR Imaging
Enabling the imaging and measurement of intrinsic dissolution and release rates using very small sample amounts.
Biorelevant Dissolution
Pion can characterise dissolution and solubility behaviour in biorelevant media simulating different zones and compositions within the human body.
Biphasic Dissolution
Pion has developed a biphasic dissolution assay to mimic dissolution and absorption within the human gastrointestinal tract (GIT).
Scientific Instruments
We provide novel in-vitro tools that promote quicker, more informed decision-making.
Resource Library
Latest citations of Pion instruments and services in industry white papers, webinars, videos, and case studies.