Webinar: "The Absorption Driven Drug Formulation Concept"

Bálint Sinkó, Manager of Technology Development, and his colleague, Enikő Borbás, PhD candidate at the Budapest University of Technology and Economics, will demonstrate the Absorption Driven Drug Formulation concept, which is a new approach in formulation development to ensure that the drug product meets the expected absorption rate. The demonstrated concept is built on the solubility-permeability interplay and the rate of supersaturation as the driving force of absorption that are detailed extensively. Various case studies will be also presented on excipient selection methods and formulation strategy optimization and how these methods can be incorporated in the complex process of formulation development. Several examples utilizing multiple assay setups will be also shown in order to demonstrate the characterization of the final formulations before in vivo studies are conducted.

Upon completion, participants will:

• understand the Absorption Driven Drug Formulation concept.
• have seen examples of drug supersaturation and its impact on absorption.
• have learn about the solubility-permeability interplay and free drug concentration.