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Drug Discovery Chemistry

All drug development programs need efficient Discovery phases in order to screen potential candidates in timely and effective ways. Well-founded Discovery strikes a balance between eliminating those candidates where the profile makes development more challenging than it is worth, and others where the therapeutic possibilities and initial analyses are so promising that pre-formulation and formulation are indicated.

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Formulation

With Discovery and Pre-Formulation studies complete, your API is ready to move into formulation development, and Pion has the equipment and expertise to help you characterise the drugs that you take into further testing.

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Pre-Formulation

Once the Discovery phase has identified promising candidates for development, it is essential to carry out comprehensive Pre-formulation studies, if successful drug development is to result.  Until the behaviour of a new API has been analysed and stress-tested under various conditions, it is impossible to progress to a robust dosage form. Pion works with companies and academic departments around the world to support Pre-formulation studies. We’ll provide the test results to inform your research, together with analysis and interpretation, if required.

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