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Resource Library

Pion experts keep you informed with precise, accessible resources on a range of topics. Browse below to see how to optimize your equipment and research methods. Alternatively filter by your interest area. In addition we are delighted to bring you published resources from reliable and relevant experts. Browse below for articles and features recommended by Pion or filter your search for specific applications, products, or formats.

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Biorelevant Flux Measurements And Prediction Of Fraction Absorbed For The Drug Products Of Poorly Soluble Compounds Biorelevant Flux Measurements And Prediction Of Fraction Absorbed For The Drug Products Of Poorly Soluble Compounds

It was demonstrated that Flux measurements provided more in-depth understanding of supersaturated concentartions than solute concentration measurements alone. 

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Tailored on demand anti-coagulant dosing: An in vitro and in vivo evaluation of 3D printed purpose-designed oral dosage forms Tailored on demand anti-coagulant dosing: An in vitro and in vivo evaluation of 3D printed purpose-designed oral dosage forms

Coumarin therapy has been associated with high levels of inter- and intra-individual variation in the required dose to reach a therapeutic anticoagulation outcome. Therefore, a dynamic system that is able to achieve accurate delivery of a warfarin dose is of significant importance.

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Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states

When developing bio-enabling formulations, innovative tools are required to understand and predict in vivo performance and may facilitate approval by regulatory authorities.

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Comparison of Cinchona Catalysts Containing Ethyl or Vinyl or Ethynyl Group at Their Quinuclidine Ring Comparison of Cinchona Catalysts Containing Ethyl or Vinyl or Ethynyl Group at Their Quinuclidine Ring

Numerous cinchona organocatalysts with different substituents at their quinuclidine unit have been described and tested, but the effect of those saturation has not been examined before. 

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pKa and physchem property measurements for the pharmaceutical industry pKa and physchem property measurements for the pharmaceutical industry

pKa is a core competence of Pion, and we have many methods for measuring it. This webinar explains the concepts of pKa measurement, the experimental means of measuring it, and the key role that this property plays in the behavior of drugs.

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WEBINAR: How pKa Values are used in the Pharmaceutical Industry

We have previously shown you how we measure pKa. This follow on webinar will describe why pKa is considered such a critical measurement in drug discovery and development environments.

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WEBINAR: Understanding and Measuring pKa

This is our first pKa webinar. In it, we describe the origins of the measurement, the origins of the science we use for our measurement platform and show you some of the extremely accurate data generated by the Pion SiriusT3

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Webinar: AuPRO™ Version 6.0: New Powerful Tools for Pion’s Fiber Optic Users

An informational webinar from our Chief Scientific Officer, Konstantin Tsinman, on Pion's new software, AuPRO 6.0. This new version is Windows 10 compatible and will also enable fiber optic users with some other powerful tools.

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AuPRO Comparison Flyer

AuPRO 6.0 software now offers several features to enhance the analysis of your compounds, secure your system (Windows 10 Compatible), and make your sample process more efficient.

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Effect of preparation method on the surface properties and UV imaging of indomethacin solid dispersions

This work explores the use of UV imaging in solid dispersion systems.

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