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Resource Library

Pion experts keep you informed with precise, accessible resources on a range of topics. Browse below to see how to optimize your equipment and research methods. Alternatively filter by your interest area. In addition we are delighted to bring you published resources from reliable and relevant experts. Browse below for articles and features recommended by Pion or filter your search for specific applications, products, or formats.

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"Utilizing Pion's SiriusT3 Platform" Webinar "Utilizing Pion's SiriusT3 Platform" Webinar

Dr. Rebeca Ruiz, Pion Analytical Services Manager, and Dr. Clara Rafols from the University of Barcelona present applications using the SiriusT3 which measures pKa, log P, log D and solubility of ionizable, small molecule drugs using sub-milligram quantities of sample.

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Analytical Services Brochure Analytical Services Brochure

Drug development can be a complex, multi-faceted challenge – so finding effective scientific support can be critical to making progress. More and more organizations are turning to Pion Analytical Services, for the tests, assays, analysis and interpretation required at all the key phases of drug development.

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"Small Scale in vitro Techniques as Predictive Tools for in vivo Performance" Webinar "Small Scale in vitro Techniques as Predictive Tools for in vivo Performance" Webinar

Pion is delighted to have Dr. Corinne Jankovsky from Boehringer Ingelheim present work she and her colleagues have done using small scale in vitro techniques as predictive tools for in vivo performance and how they have incorporated Pion technology to guide formulation design.

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"Simulating Biologic Post Injection Events Utilizing the Pion Scissor" Webinar "Simulating Biologic Post Injection Events Utilizing the Pion Scissor" Webinar

Join us as Imogen Knight, Biopharmaceutical Product Specialist at Pion Inc, provides examples of biologic post injection event simulations utilizing the Pion Scissor.

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"miniDISS Profiler Including the *NEW* miniDT" Webinar "miniDISS Profiler Including the *NEW* miniDT" Webinar

Small volume dissolution testing has been an integral part of the global drug development process for decades. Now, with the launch of the Pion MiniDISS Profiler, the industry has a dedicated platform to perform this type of testing. Please join us as Pion Product Manager, Ken Caldwell, describes this new product in detail.

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"SDi2: Unlocking the Secrets of Your Dissolution" Webinar "SDi2: Unlocking the Secrets of Your Dissolution" Webinar

Join Andrew Kennedy, Pion Analytical Services Scientist II, as he unlocks the unseen secrets of your dissolution studies, using the Pion SDi2 to image the dissolution processes occurring at the surface of your samples. Andrew obtained a Master's in Chemistry from the University of Warwick in 2017. He joined Pion in 2018 and has developed expertise in the Pion SDi2 and across the entire range of Pion’s analytical tools while carrying out a wide variety of analyses for our partners across the pharmaceutical industry.

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"Pion MacroFLUX for Predictive Dissolution Absorption Measurements" Webinar "Pion MacroFLUX for Predictive Dissolution Absorption Measurements" Webinar

Haotian Wang presents the flux measurements that incorporate absorption steps to better understand complex dissolution-absorption interplay in formulation development and generic drug evaluation. 

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"Pion's Analytical Services" Webinar "Pion's Analytical Services" Webinar

Dr. Rebeca Ruiz presents an overview of Pion's Analytical Services group and the ways we can help your pharmaceutical drug formulation and drug development.

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"Pion Biphasic Dissolution  PBPK Modelling and Lipolysis Assays" Webinar "Pion Biphasic Dissolution PBPK Modelling and Lipolysis Assays" Webinar

Pion Chief Technical Officer - Europe, Karl Box, and Dr. Patrick O'Dwyer from the University of Cork, present applications in biphasic dissolution. 

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Application of Focus Variation Microscopy and Dissolution Imaging in Understanding the Behaviour of Hydrophilic Matrices Application of Focus Variation Microscopy and Dissolution Imaging in Understanding the Behaviour of Hydrophilic Matrices

Hydrophilic matrix systems can be found in a wide range of extended release pharmaceutical formulations. The main principle of these systems is that upon contact with water, the hydrophilic component swells to form a hydrated gel layer which controls drug release. The following work demonstrates an explorative study into the use of surface dissolution imaging and focus variation microscopy with hydrophilic polymers. This study investigated the surface properties of xanthan gum (XG), polyethylene oxide (PEO), and hypromellose (hydroxypropyl methylcellulose, HPMC) compacts with each of these three hydrophilic polymers from one of each classification of natural, semi-synthetic, or synthetic polymer using a focus variation instrument.

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