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Resource Library

Pion experts keep you informed with precise, accessible resources on a range of topics. Browse below to see how to optimize your equipment and research methods. Alternatively filter by your interest area. In addition we are delighted to bring you published resources from reliable and relevant experts. Browse below for articles and features recommended by Pion or filter your search for specific applications, products, or formats.

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LabEye LabEye | A ready-to-implement multi-camera system performing visual process monitoring

Designed specifically for laboratory use, the LabEye is a ready-to-implement multi-camera system performing visual process monitoring, chronicling research in HD clarity and providing automation troubleshooting.

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Single or multi-station blending platform that speeds up the content uniformity sample preparation process. Pion PrepEngine | Single or multi-station content uniformity blending platform.

PrepEngine is a Flexible Life Science Processing Platform that can Extract Materials into Solution, Mix, Centrifuge, Lyse and more. 

PrepEngine is Modular and is ready to add automation and control to your process. With modules for extraction, mixing, centrifugation, lysing, and more, you’ll be able to overcome your toughest challenges.

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VIDEO: Membrane Flux in-vitro : BioFLUX, MacroFLUX, MicroFLUX VIDEO: Membrane Flux in-vitro : BioFLUX, MacroFLUX, MicroFLUX

Evaluate the absorption potential of your drug compounds. Bridging the gap between in vitro experiments and in vivo outcomes.

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Trends in oral small-molecule drug discovery and product development based on product launches before and after the Rule of Five” Trends in oral small-molecule drug discovery and product development based on product launches before and after the Rule of Five”

Formulation and drug delivery technology play an important role in oral drug product development.

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Methodological Considerations in Development of UV Imaging for Characterization of Intra-Tumoral Injectables Using cAMP as a Model Substance Methodological Considerations in Development of UV Imaging for Characterization of Intra-Tumoral Injectables Using cAMP as a Model Substance

The UV imaging and MATLAB data analysis setup constituted a significant technical development in terms of visualizing behavior for injectable formulations intended for intra-tumoral delivery, and, thereby, a step toward the establishment of a bio-predictive in vitro release-testing method.

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Unveiling Solubility, Dissolution and Permeability In Vitro: How GSK Sees the (UV) Light Unveiling Solubility, Dissolution and Permeability In Vitro: How GSK Sees the (UV) Light

This webinar will describe how Pion’s instruments are providing effective dissolution studies and risk analyses during GSK’s drug development pipeline, and how you can also leverage these technologies in your drug formulation R&D approaches.

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Preparation and advanced characterization of highly drug-loaded, 3D printed orodispersible tablets containing fluconazole Preparation and advanced characterization of highly drug-loaded, 3D printed orodispersible tablets containing fluconazole

The goal of the work done here was the preparation and advanced characterization of 3D printed orodispersible tablets (ODTs) containing fluconazole, printed by the fused deposition modeling (FDM) method.

Using Pion's SDi2 surface dissolution imaging system to evaluate the erosion and swelling behavior of the tablets with hydrophilic matrices, or hard galantine capsules filled with solid dispersions.

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Virtual Cocrystal Screening of Adefovir Dipivoxyl: Identification of New Solid Forms with Improved Dissolution and Permeation Profiles Virtual Cocrystal Screening of Adefovir Dipivoxyl: Identification of New Solid Forms with Improved Dissolution and Permeation Profiles

This article describes the use of Pion's inForm platform to simulate the transition in the gastrointestinal tract and the permeation to the biological membranes. This is a collaboration between Pion Inc. and the University of Barcelona.

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Enabling SEDDS Formulation Choice through In Vitro-In Vivo Correlation with BASF and Pion Enabling SEDDS Formulation Choice through In Vitro-In Vivo Correlation with BASF and Pion

SEDDS formulations consist of complex mixtures of lipid-surfactant agents in order to match the target interfacial tension.  The absorption rate of the Active Pharmaceutical Ingredient (API) can be enhanced by fine tuning the composition of SEDDS.

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Lessons-learned Advanced in vitro methods in generic drug product development

Zentiva is a generics manufacturer that is developing innovative processes to manufacture APIs, and to formulate the drug product itself.  It is using Pion instruments to better understand the API molecule’s behavior in-vivo and any potential risks to progression are critical in the development of new generic medicines.

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