Optimizing drug development with innovative instruments & scientific expertise

New and Exciting from Pion

 

An upcoming publication in the International Journal of Pharmaceutics investigates using the Parallel Artificial Membrane Permeation Assay (PAMPA) model to assess in vitro skin penetration of pharmaceutical or cosmetic ingredients without using human or animal tissue.

A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model

New research from the University of Kansas using Pion’s Scissor technology to test subcutaneous injections of Glatiramer Acetate, the active ingredient in Copaxone®, was published in the Journal of Controlled Release.

Glatiramer Acetate Persists at the Injection Site and Draining Lymph Nodes via Electrostatically-Induced Aggregation

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January 2018

Preclinical Development & IND/CTA Filing

January 22, 2018 @ 8:30 am - 5:00 pm
Free – $195

In this workshop, our speakers highly experienced with IND filings will discuss systemically the preclinical studies required for small molecule IND filings and the nuts, bolts, and best practices for putting together a high-quality IND package, as well as how to interact with various regulatory agencies.

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February 2018

Biorelevant?

February 21, 2018 @ 6:00 pm - February 22, 2018 @ 5:30 pm
Carlsberg Conference Center, Gamle Carlsberg Vej 15
København, 1799 Denmark
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$400

A 1-dygn* symposium to discuss and debate biorelevant assays in Pharmaceutical Science

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June 2018

2018 UKICRS Workshop & Symposium

June 4, 2018 - June 5, 2018
Riddel Hall, 185 Stranmillis Road
Belfast, Northern Ireland BT9 5EE United Kingdom
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The UKICRS Symposium is primarily aimed at postgraduate students, postdoctoral research fellows, industrialists and academics working in the the fields of pharmaceutical sciences and drug delivery. The symposium will offer a wide range of opportunities for both young and established scientists to present their latest research and network with others from academia and industry.

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Advancing Drug Development – San Francisco

June 14, 2018 @ 8:00 am - 8:30 pm
San Francisco Wine School, 415 Grand Avenue, Suite 301
San Francisco, CA 94080 United States
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The Inaugural West Coast Advancing Drug Development Forum - Making the Impossible, Possible. Like ‘The Inaugural Advancing Drug Development Forum - Making the Impossible, Possible that took place in December in Boston, this inaugural west coast forum program aims to bring together key opinion leaders in biotech and pharma, executive leadership, senior directors, consultants, and a close network of non-competitive CROs and CDMOs to explore together novel solutions, promising technology breakthroughs and how industry introduces and incorporates improved approaches in small molecule drug development. 

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Recommended Resources

ImageTitle
A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model
A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model
Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation
Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation
Using pH Gradient Dissolution with In-Situ Flux Measurement to Evaluate Bioavailability and DDI for Formulated Poorly Soluble Drug Products
Using pH Gradient Dissolution with In-Situ Flux Measurement to Evaluate Bioavailability and DDI for Formulated Poorly Soluble Drug Products
Determination of pKa values and Solubility pH Profiles of Selected ß blockers
Determination of pKa values and Solubility pH Profiles of Selected ß blockers
AN10 Measuring LogP of Samples that are Hard to Dissolve in Water and Octanol
AN10 Measuring LogP of Samples that are Hard to Dissolve in Water and Octanol
AN410 Measuring the isoelectric point pf peptides by potentiometric titration
AN410 Measuring the isoelectric point pf peptides by potentiometric titration
AN402 Controlled supersaturation assays for modelling intestinal precipitation
AN402 Controlled supersaturation assays for modelling intestinal precipitation
Application of MacroFLUX™ Apparatus for Screening Formulations before Bioequivalent Studies
Application of MacroFLUX™ Apparatus for Screening Formulations before Bioequivalent Studies
Using flux experiments through artificial lipophilic membranes for predicting food effect for BCS Class 2 Compounds
Using flux experiments through artificial lipophilic membranes for predicting food effect for BCS Class 2 Compounds
Studying semi-solid formulations of diclofenac using Skin PAMPA
Studying semi-solid formulations of diclofenac using Skin PAMPA
Degree and Extent of Supersaturation of Amorphous Pharmaceuticals and Their Flux through Lipophilic Membranes
Degree and Extent of Supersaturation of Amorphous Pharmaceuticals and Their Flux through Lipophilic Membranes

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Most Popular Resources

ImageTitleDisplay Order
Scissor subcutaneous poster
Scissor subcutaneous poster3
Subcutaneously administered biopharmaceuticals
Subcutaneously administered biopharmaceuticals5
MacroFLUX Generics
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Measuring Physiochemical Properties 24
pKa and physchem property measurements for the pharmaceutical industry
pKa and physchem property measurements for the pharmaceutical industry6
WEBINAR: How pKa Values are used in the Pharmaceutical Industry
WEBINAR: How pKa Values are used in the Pharmaceutical Industry1
WEBINAR: Understanding and Measuring pKa
WEBINAR: Understanding and Measuring pKa2

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