Fiber optic dissolution is the quicker, more reliable alternative for large or difficult data sets.
Traditional dissolution takes place in extremely large vessels (typically 900mL). Whilst this is entirely appropriate for applications such as QC testing of marketed drugs, it can be a limitation when it comes to applications such as formulation development where fast measurements are required using much smaller amounts of API or formulated API.
Pion has developed extremely powerful techniques for scientists working in discovery, preformulation and formulation which operate using smaller amounts of sample, and offer numerous proprietary assay types developed specifically for users like you.
Traditional testing is also conducted by manually removing samples from dissolution vessels and using a UV spectrometer or HPLC for testing. With fiber optics, real-time drug release level is determined in-situ in your vessels, in real-time and without any removal of samples. The labor-intensive manual sampling procedure is completely eliminated and, therefore, the testing procedure is simplified.
With over 15 years on the market, Pion’s fiber optic technology is the benchmark of reliability. Ten out of ten of the top pharmaceutical companies use Pion’s fiber optic technology for their in-situ UV monitoring needs. Pion’s fiber optic technology is a flexible and reliable tool for determining the rate of release of a drug substance over time.