Combining the data from a dissolution experiment with trans-membrane permeation, the µFLUX™ system is the perfect tool for making early pharmacokinetic decisions.

Whether assessing the effect different formulation vehicles have on FLUX, or assessing pre-clinical performance based on pH or food, Pion’s µFLUX™ is a convenient and powerful in vitro tool. This novel solution will allow you to easily conduct small volume, in situ concentration monitoring, and at the same time evaluate the absorption potential of your compound as you separate the receiver and donor chambers with a membrane. The µFLUX™ also allows you to control for temperature and stirring.






Case Studies 



Case Study 1: Formulation FLUX Enhancement Case Study 2: Formulation FLUX Inhibition Case Study 3: FLUX Effect of Supersaturation




View this poster from AAPS describing the µFLUX set up



 Case Study 1-Formulation FLUX Enhancement

 Case Study 2-Formulation FLUX Inhibition

 Case Study 3-FLUX Effect of Supersaturation

Additional Resources